ATP7B knockout disturbs copper and lipid metabolism in Caco-2 cells

Intestinal cells control delivery of lipids to the body by adsorption, storage and secretion. Copper (Cu) is an important trace element and has been shown to modulate lipid metabolism. Mutation of the liver Cu exporter ATP7B is the cause of Wilson disease and is associated with Cu accumulation in di...

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Udgivet i:PLoS One
Main Authors: Guttmann, Sarah, Nadzemova, Oksana, Grünewald, Inga, Lenders, Malte, Brand, Eva, Zibert, Andree, Schmidt, Hartmut H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064347/
https://ncbi.nlm.nih.gov/pubmed/32155648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230025
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