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Novel Antiparasitic Activity of the Antifungal Lead Occidiofungin

Novel antiparasitic activity was observed for the antifungal occidiofungin. It efficaciously and irreversibly inhibited the zoonotic enteric parasite Cryptosporidium parvum in vitro with limited cytotoxicity (50% effective concentration [EC(50)] = 120 nM versus 50% cytotoxic concentration [TC(50)] =...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Ma, Jingbo, Guo, Fengguang, Jin, Zi, Geng, Mengxin, Ju, Min, Ravichandran, Akshaya, Orugunty, Ravi, Smith, Leif, Zhu, Guan, Zhang, Haili
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526809/
https://ncbi.nlm.nih.gov/pubmed/32457108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00244-20
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