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Novel Antiparasitic Activity of the Antifungal Lead Occidiofungin

Novel antiparasitic activity was observed for the antifungal occidiofungin. It efficaciously and irreversibly inhibited the zoonotic enteric parasite Cryptosporidium parvum in vitro with limited cytotoxicity (50% effective concentration [EC(50)] = 120 nM versus 50% cytotoxic concentration [TC(50)] =...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ma, Jingbo, Guo, Fengguang, Jin, Zi, Geng, Mengxin, Ju, Min, Ravichandran, Akshaya, Orugunty, Ravi, Smith, Leif, Zhu, Guan, Zhang, Haili
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526809/
https://ncbi.nlm.nih.gov/pubmed/32457108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00244-20
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