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Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure
AIMS: Cardiac myocyte hypertrophy, the main compensatory response to chronic stress in the heart often progresses to a state of decompensation that can lead to heart failure. Osteopontin (OPN) is an effector for extracellular signalling that induces myocyte growth and fibrosis. Although increased OP...
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| Publicado en: | Cardiovasc Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7526752/ https://ncbi.nlm.nih.gov/pubmed/28453726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx016 |
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