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Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure

AIMS: Cardiac myocyte hypertrophy, the main compensatory response to chronic stress in the heart often progresses to a state of decompensation that can lead to heart failure. Osteopontin (OPN) is an effector for extracellular signalling that induces myocyte growth and fibrosis. Although increased OP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cardiovasc Res
Päätekijät: Li, Jihe, Yousefi, Keyvan, Ding, Wen, Singh, Jayanti, Shehadeh, Lina A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526752/
https://ncbi.nlm.nih.gov/pubmed/28453726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx016
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