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Lentivirus Manufacturing Process for Primary T-cell Biofactory Production

A process for maximizing the titer of lentivirus particles, deemed to be a necessity for transducing primary cells, has been developed. Lentivirus particles, with a set of transgenes encoding an artificial cell-signaling pathway, were used to transform primary T cells as vectors for calibrated synth...

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Foilsithe in:Adv Biosyst
Main Authors: Radhakrishnan, Harikrishnan, Javitz, Harold S., Bhatnagar, Parijat
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526617/
https://ncbi.nlm.nih.gov/pubmed/32390316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.201900288
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