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Manufacture of Third-Generation Lentivirus for Preclinical Use, with Process Development Considerations for Translation to Good Manufacturing Practice

Lentiviral vectors are used in laboratories around the world for in vivo and ex vivo delivery of gene therapies, and increasingly clinical investigation as well as preclinical applications. The third-generation lentiviral vector system has many advantages, including high packaging capacity, stable g...

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Detalles Bibliográficos
Publicado en:Hum Gene Ther Methods
Main Authors: Gándara, Carolina, Affleck, Valerie, Stoll, Elizabeth Ann
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806069/
https://ncbi.nlm.nih.gov/pubmed/29212357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2017.098
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