Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

In order to prioritize available immune therapeutics, immune profiling across glioma grades was conducted, followed by preclinical determinations of therapeutic effect in immune-competent mice harboring gliomas. T cells and myeloid cells were isolated from the blood of healthy donors and the blood a...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Ott, Martina, Tomaszowski, Karl-Heinz, Marisetty, Anantha, Kong, Ling-Yuan, Wei, Jun, Duna, Maya, Blumberg, Katia, Ji, Xiaorong, Jacobs, Carmen, Fuller, Gregory N., Langford, Lauren A., Huse, Jason T., Long, James P., Hu, Jian, Li, Shulin, Weinberg, Jeffrey S., Prabhu, Sujit S., Sawaya, Raymond, Ferguson, Sherise, Rao, Ganesh, Lang, Frederick F., Curran, Michael A., Heimberger, Amy B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526457/
https://ncbi.nlm.nih.gov/pubmed/32721947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134386
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