Multiomics dissection of molecular regulatory mechanisms underlying autoimmune-associated noncoding SNPs

More than 90% of autoimmune-associated variants are located in noncoding regions, leading to challenges in deciphering the underlying causal roles of functional variants and genes and biological mechanisms. Therefore, to reduce the gap between traditional genetic findings and mechanistic understandi...

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Vydáno v:JCI Insight
Hlavní autoři: Chen, Xiao-Feng, Guo, Ming-Rui, Duan, Yuan-Yuan, Jiang, Feng, Wu, Hao, Dong, Shan-Shan, Zhou, Xiao-Rong, Thynn, Hlaing Nwe, Liu, Cong-Cong, Zhang, Lin, Guo, Yan, Yang, Tie-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526455/
https://ncbi.nlm.nih.gov/pubmed/32879140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136477
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