Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer’s disease

BACKGROUND: Hypothalamic dysfunction occurs early in the clinical course of Alzheimer’s disease (AD), likely contributing to disturbances in feeding behavior and metabolic function that are often observed years prior to the onset of cognitive symptoms. Late-life weight loss and low BMI are associate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neuroinflammation
Egile Nagusiak: Robison, Lisa S., Gannon, Olivia J., Thomas, Melissa A., Salinero, Abigail E., Abi-Ghanem, Charly, Poitelon, Yannick, Belin, Sophie, Zuloaga, Kristen L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526387/
https://ncbi.nlm.nih.gov/pubmed/32993686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01956-5
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