Integrated analysis of the aging brain transcriptome and proteome in tauopathy

BACKGROUND: Tau neurofibrillary tangle pathology characterizes Alzheimer’s disease and other neurodegenerative tauopathies. Brain gene expression profiles can reveal mechanisms; however, few studies have systematically examined both the transcriptome and proteome or differentiated Tau- versus age-de...

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Pubblicato in:Mol Neurodegener
Autori principali: Mangleburg, Carl Grant, Wu, Timothy, Yalamanchili, Hari K., Guo, Caiwei, Hsieh, Yi-Chen, Duong, Duc M., Dammer, Eric B., De Jager, Philip L., Seyfried, Nicholas T., Liu, Zhandong, Shulman, Joshua M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526226/
https://ncbi.nlm.nih.gov/pubmed/32993812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00405-4
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