Integrated analysis of the aging brain transcriptome and proteome in tauopathy

BACKGROUND: Tau neurofibrillary tangle pathology characterizes Alzheimer’s disease and other neurodegenerative tauopathies. Brain gene expression profiles can reveal mechanisms; however, few studies have systematically examined both the transcriptome and proteome or differentiated Tau- versus age-de...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Mangleburg, Carl Grant, Wu, Timothy, Yalamanchili, Hari K., Guo, Caiwei, Hsieh, Yi-Chen, Duong, Duc M., Dammer, Eric B., De Jager, Philip L., Seyfried, Nicholas T., Liu, Zhandong, Shulman, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526226/
https://ncbi.nlm.nih.gov/pubmed/32993812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00405-4
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