Genetic polymorphisms and dosing of vitamin K antagonist in Indian patients after heart valve surgery

PURPOSE: Vitamin K antagonists (VKAs), such as warfarin and acenocoumarol, exert their anti-coagulant effect by inhibiting the subunit 1 of vitamin K epoxide reductase complex (VKORC1). CYP2C9 is a hepatic drug-metabolizing enzyme in the CYP450 superfamily and is the primary metabolizing enzyme of w...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Indian J Thorac Cardiovasc Surg
Main Authors: Choudhary, Shiv Kumar, Mathew, Arun Basil, Parhar, Amit, Hote, Milind Padmakar, Talwar, Sachin, Rajashekhar, Palleti
Format: Artigo
Jezik:Inglês
Izdano: Springer Singapore 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525906/
https://ncbi.nlm.nih.gov/pubmed/33061049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12055-019-00812-3
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