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Genetic polymorphisms and dosing of vitamin K antagonist in Indian patients after heart valve surgery
PURPOSE: Vitamin K antagonists (VKAs), such as warfarin and acenocoumarol, exert their anti-coagulant effect by inhibiting the subunit 1 of vitamin K epoxide reductase complex (VKORC1). CYP2C9 is a hepatic drug-metabolizing enzyme in the CYP450 superfamily and is the primary metabolizing enzyme of w...
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| 出版年: | Indian J Thorac Cardiovasc Surg |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Singapore
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7525906/ https://ncbi.nlm.nih.gov/pubmed/33061049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12055-019-00812-3 |
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