Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation

Tissue homeostasis relies on the fine regulation between stem and progenitor cell maintenance and lineage commitment. In the adult prostate, stem cells have been identified in both basal and luminal cell compartments. However, basal stem/progenitor cell homeostasis is still poorly understood. We sho...

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Bibliographic Details
Published in:eLife
Main Authors: Tremblay, Mathieu, Viala, Sophie, Shafer, Maxwell ER, Graham-Paquin, Adda-Lee, Liu, Chloe, Bouchard, Maxime
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Stem Cells and Regenerative Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525654/
https://ncbi.nlm.nih.gov/pubmed/32894216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54542
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