Mac-2-binding protein glycan isomer enhances the aggressiveness of hepatocellular carcinoma by activating mTOR signaling

BACKGROUND: Wisteria floribunda agglutinin (WFA)(+) Mac-2-binding protein (M2BPGi) is a novel serum marker for liver fibrosis. Although an elevated serum level of M2BPGi can predict development of hepatocellular carcinoma (HCC), the effect of M2BPGi on HCC remains unclear. There are no reports about...

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Publicado no:Br J Cancer
Main Authors: Dolgormaa, Gantumur, Harimoto, Norifumi, Ishii, Norihiro, Yamanaka, Takahiro, Hagiwara, Kei, Tsukagoshi, Mariko, Igarashi, Takamichi, Watanabe, Akira, Kubo, Norio, Araki, Kenichiro, Handa, Tadashi, Yokobori, Takehiko, Oyama, Tetsunari, Kuwano, Hiroyuki, Shirabe, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525442/
https://ncbi.nlm.nih.gov/pubmed/32624579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0971-y
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