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Harnessing endogenous repair mechanisms for targeted gene knock-in of bovine embryos

Introducing useful traits into livestock breeding programs through gene knock-ins has proven challenging. Typically, targeted insertions have been performed in cell lines, followed by somatic cell nuclear transfer cloning, which can be inefficient. An alternative is to introduce genome editing reage...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Owen, Joseph R., Hennig, Sadie L., McNabb, Bret R., Lin, Jason C., Young, Amy E., Murray, James D., Ross, Pablo J., Van Eenennaam, Alison L.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525238/
https://ncbi.nlm.nih.gov/pubmed/32994506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72902-x
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