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Harnessing endogenous repair mechanisms for targeted gene knock-in of bovine embryos
Introducing useful traits into livestock breeding programs through gene knock-ins has proven challenging. Typically, targeted insertions have been performed in cell lines, followed by somatic cell nuclear transfer cloning, which can be inefficient. An alternative is to introduce genome editing reage...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7525238/ https://ncbi.nlm.nih.gov/pubmed/32994506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72902-x |
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