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Limonene-induced activation of A(2A) adenosine receptors reduces airway inflammation and reactivity in a mouse model of asthma

Animal models of asthma have shown that limonene, a naturally occurring terpene in citrus fruits, can reduce inflammation and airway reactivity. However, the mechanism of these effects is unknown. We first performed computational and molecular docking analyses that showed limonene could bind to both...

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Vydáno v:Purinergic Signal
Hlavní autoři: Patel, Mehaben, Narke, Deven, Kurade, Mangesh, Frey, Kathleen M., Rajalingam, Sahith, Siddiquee, Armaan, Mustafa, S Jamal, Ledent, Catherine, Ponnoth, Dovenia S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524888/
https://ncbi.nlm.nih.gov/pubmed/32789792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09697-z
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