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Favorable therapeutic response after anti-Mesothelin antibody–drug conjugate treatment requires high expression of Mesothelin in tumor cells

PURPOSE: The cell surface glycoprotein Mesothelin is overexpressed in ovarian, fallopian tube, endometrial, cervical and primary peritoneal cancer and, therefore, might become a particular interesting tumor target in gynecologic oncology. However, even in malignant tumors of the same entity the leve...

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Publicat a:Arch Gynecol Obstet
Autors principals: Lazzerini, Lea, Jöhrens, Korinna, Sehouli, Jalid, Cichon, Günter
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524828/
https://ncbi.nlm.nih.gov/pubmed/32815024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00404-020-05734-9
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