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Novel Antibody Therapeutics Targeting Mesothelin In Solid Tumors

ABSTRACT: BACKGROUND: Monoclonal antibodies have become attractive clinical anti-cancer drugs in the last 3 decades due to their targeting specificity and suitable pharmacokinetic properties. Mesothelin is a tumor-associated antigen with limited expression in normal tissues. It is frequently over-ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Drugs
Hauptverfasser: Zhao, Xiao-Yan, Subramanyam, Babu, Sarapa, Nenad, Golfier, Sven, Dinter, Harald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080863/
https://ncbi.nlm.nih.gov/pubmed/27853672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212697X03666160218215744
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