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Amatuximab and novel agents targeting mesothelin for solid tumors

Mesothelin (MSLN) is considered a promising target for cancer therapy. Originally extracted in 1992 after the immunization of mice with a human ovarian cancer (OC) cell line and cloned in 1996, MSLN seems to be involved in cell adhesion and metastasis. MSLN is prevalent in mesothelia tissues but is...

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Bibliografski detalji
Izdano u:Onco Targets Ther
Glavni autori: Baldo, Paolo, Cecco, Sara
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687483/
https://ncbi.nlm.nih.gov/pubmed/29184420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S145105
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