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Amatuximab and novel agents targeting mesothelin for solid tumors
Mesothelin (MSLN) is considered a promising target for cancer therapy. Originally extracted in 1992 after the immunization of mice with a human ovarian cancer (OC) cell line and cloned in 1996, MSLN seems to be involved in cell adhesion and metastasis. MSLN is prevalent in mesothelia tissues but is...
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Publicado no: | Onco Targets Ther |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Dove Medical Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5687483/ https://ncbi.nlm.nih.gov/pubmed/29184420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S145105 |
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