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Dual COX and 5-LOX inhibition by clerodane diterpenes from seeds of Polyalthia longifolia (Sonn.) Thwaites

Natural metabolites with their specific bioactivities are being considered as a potential source of materials for pharmacological studies. In this study, we successfully isolated and identified five known clerodane diterpenes, namely 16-oxo-cleroda-3,13(14)E-dien-15-oic acid (1), 16-hydroxy-cleroda-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nguyen, Ha Thi, Vu, Thien-Y., Chandi, Vishala, Polimati, Haritha, Tatipamula, Vinay Bharadwaj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524750/
https://ncbi.nlm.nih.gov/pubmed/32994508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72840-8
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