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γH2AX in the S Phase after UV Irradiation Corresponds to DNA Replication and Does Not Report on the Extent of DNA Damage

Ultraviolet (UV) radiation is a major environmental mutagen. Exposure to UV leads to a sharp peak of γH2AX, the phosphorylated form of the histone variant H2AX, in the S phase within an asynchronous population of cells. γH2AX is often considered a definitive marker of DNA damage inside a cell. In th...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Dhuppar, Shivnarayan, Roy, Sitara, Mazumder, Aprotim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523655/
https://ncbi.nlm.nih.gov/pubmed/32778572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00328-20
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