Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

Oxidative stress is a central part of innate-immune induced neurodegeneration. However, the transcriptomic landscape of the central nervous system (CNS) innate immune cells contributing to oxidative stress is unknown, and therapies to target their neurotoxic functions are not widely available. Here,...

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Publicado no:Nat Immunol
Main Authors: Mendiola, Andrew S., Ryu, Jae Kyu, Bardehle, Sophia, Meyer-Franke, Anke, Ang, Kenny Kean-Hooi, Wilson, Chris, Baeten, Kim M., Hanspers, Kristina, Merlini, Mario, Thomas, Sean, Petersen, Mark A., Williams, Alexander, Thomas, Reuben, Rafalski, Victoria A., Meza-Acevedo, Rosa, Tognatta, Reshmi, Yan, Zhaoqi, Pfaff, Samuel J., Machado, Michael R., Bedard, Catherine, Coronado, Pamela E. Rios, Jiang, Xiqian, Wang, Jin, Pleiss, Michael A., Green, Ari J., Zamvil, Scott S., Pico, Alexander R., Bruneau, Benoit G., Arkin, Michelle R., Akassoglou, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523413/
https://ncbi.nlm.nih.gov/pubmed/32284594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0654-0
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