Microparticles derived from human erythropoietin mRNA-transfected mesenchymal stem cells inhibit epithelial-to-mesenchymal transition and ameliorate renal interstitial fibrosis

BACKGROUND: Renal tubulointerstitial fibrosis (TIF) plays an important role in the progression of chronic kidney disease (CKD) and its pathogenesis involves epithelial-to-mesenchymal transition (EMT) upon renal injury. Recombinant human erythropoietin (rhEPO) has been shown to display novel cytoprot...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Lee, Mirae, Kim, Seok-hyung, Jhee, Jong Hyun, Kim, Tae Yeon, Choi, Hoon Young, Kim, Hyung Jong, Park, Hyeong Cheon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523343/
https://ncbi.nlm.nih.gov/pubmed/32993806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01932-z
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