Microparticles derived from human erythropoietin mRNA-transfected mesenchymal stem cells inhibit epithelial-to-mesenchymal transition and ameliorate renal interstitial fibrosis

BACKGROUND: Renal tubulointerstitial fibrosis (TIF) plays an important role in the progression of chronic kidney disease (CKD) and its pathogenesis involves epithelial-to-mesenchymal transition (EMT) upon renal injury. Recombinant human erythropoietin (rhEPO) has been shown to display novel cytoprot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Res Ther
Prif Awduron: Lee, Mirae, Kim, Seok-hyung, Jhee, Jong Hyun, Kim, Tae Yeon, Choi, Hoon Young, Kim, Hyung Jong, Park, Hyeong Cheon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523343/
https://ncbi.nlm.nih.gov/pubmed/32993806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01932-z
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