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Enhanced expression of synoviolin in peripheral blood from obese/overweight donors

Obesity is currently a major medical and societal issue. Synoviolin (SYVN1) is an E3 ubiquitin ligase involved in endoplasmic reticulum (ER) stress. Overexpression of Syvn1 has been found in genetically obese mice (ob/ob and db/db), and treatment with a Syvn1 inhibitor suppresses weight gain in some...

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Bibliografiska uppgifter
I publikationen:Exp Ther Med
Huvudupphovsmän: Fujita, Hidetoshi, Aratani, Satoko, Mizoguchi, Izuru, Yagishita, Naoko, Nakajima, Toshihiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523271/
https://ncbi.nlm.nih.gov/pubmed/33005247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9249
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