Identification of a Crucial Site for Synoviolin Expression

Synoviolin is an E3 ubiquitin ligase localized in the endoplasmic reticulum (ER) and serving as ER-associated degradation system. Analysis of transgenic mice suggested that synoviolin gene dosage is implicated in the pathogenesis of arthropathy. Complete deficiency of synoviolin is fatal embryonical...

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Autors principals: Tsuchimochi, Kaneyuki, Yagishita, Naoko, Yamasaki, Satoshi, Amano, Tetsuya, Kato, Yukihiro, Kawahara, Ko-ichi, Aratani, Satoko, Fujita, Hidetoshi, Ji, Fengyun, Sugiura, Akiko, Izumi, Toshihiko, Sugamiya, Asako, Maruyama, Ikuro, Fukamizu, Akiyoshi, Komiya, Setsuro, Nishioka, Kusuki, Nakajima, Toshihiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190266/
https://ncbi.nlm.nih.gov/pubmed/16055742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7344-7356.2005
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