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Genes with 5′ terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein

Viruses rely on the host translation machinery to synthesize their own proteins. Consequently, they have evolved varied mechanisms to co-opt host translation for their survival. SARS-CoV-2 relies on a non-structural protein, Nsp1, for shutting down host translation. However, it is currently unknown...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Rao, Shilpa, Hoskins, Ian, Tonn, Tori, Garcia, P. Daniela, Ozadam, Hakan, Cenik, Elif Sarinay, Cenik, Can
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523102/
https://ncbi.nlm.nih.gov/pubmed/32995776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.13.295493
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