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S6 phosphorylation-independent pathways regulate translation of 5′-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells

Synthesis of new ribosomes is an energy costly and thus highly regulated process. Ribosomal protein synthesis is controlled by regulating translation of the corresponding ribosomal protein (rp)mRNAs. In mammalian cells a 5′-terminal oligopyrimidine tract (TOP) is a conserved feature of these mRNAs t...

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Detalhes bibliográficos
Main Authors: Barth-Baus, Diane, Stratton, Carl A., Parrott, Lou, Myerson, Howard, Meyuhas, Oded, Templeton, Dennis J., Landreth, Gary E., Hensold, Jack O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113832/
https://ncbi.nlm.nih.gov/pubmed/11972328
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