FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids

Humans have undergone intense evolutionary selection to optimize their capacity to generate necessary quantities of long chain (LC-) polyunsaturated fatty acid (PUFA)-containing lipids. To better understand the impact of genetic variation within a locus of three FADS genes (FADS1, FADS2, and FADS3)...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Reynolds, Lindsay M., Dutta, Rahul, Seeds, Michael C., Lake, Kirsten N., Hallmark, Brian, Mathias, Rasika A., Howard, Timothy D., Chilton, Floyd H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522985/
https://ncbi.nlm.nih.gov/pubmed/32985521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71948-1
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