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Microencapsulation of amorphous solid dispersions of fenretinide enhances drug solubility and release from PLGA in vitro and in vivo
The purpose of this study was to develop solid dispersions of fenretinide(4HPR), incorporate them into poly (lactic-co-glycolic)(PLGA) millicylindrical implants, and evaluate the resulting implants in vitro and in vivo for future applications in oral cancer chemoprevention. Due to the extreme hydrop...
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| Publicat a: | Int J Pharm |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7522920/ https://ncbi.nlm.nih.gov/pubmed/32525080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2020.119475 |
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