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Cytosolic Crowding Drives the Dynamics of Both Genome and Cytosol in Escherichia coli Challenged with Sub-lethal Antibiotic Treatments

In contrast to their molecular mode of action, the system-level effect of antibiotics on cells is only beginning to be quantified. Molecular crowding is expected to be a relevant global regulator, which we explore here through the dynamic response phenotypes in Escherichia coli, at single-cell resol...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Wlodarski, Michal, Mancini, Leonardo, Raciti, Bianca, Sclavi, Bianca, Lagomarsino, Marco Cosentino, Cicuta, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522891/
https://ncbi.nlm.nih.gov/pubmed/33083729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101560
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