Cytosolic Crowding Drives the Dynamics of Both Genome and Cytosol in Escherichia coli Challenged with Sub-lethal Antibiotic Treatments

Summary: In contrast to their molecular mode of action, the system-level effect of antibiotics on cells is only beginning to be quantified. Molecular crowding is expected to be a relevant global regulator, which we explore here through the dynamic response phenotypes in Escherichia coli, at single-c...

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Bibliografiske detaljer
Main Authors: Michal Wlodarski, Leonardo Mancini, Bianca Raciti, Bianca Sclavi, Marco Cosentino Lagomarsino, Pietro Cicuta
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020-10-01
Serier:iScience
Fag:
Chromosome Organization
Cell Biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004220307525
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