Nerve Growth Factor Modulates TRPV1 Expression and Function and Mediates Pain in Chronic Pancreatitis

BACKGROUND & AIMS: The pathogenesis of pain in chronic pancreatitis (CP) is poorly understood and treatment remains difficult. We hypothesized that nerve growth factor (NGF) plays a key role in this process via its effects on the transient receptor potential vanilloid 1, TRPV1. METHODS: CP was i...

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Vydáno v:Gastroenterology
Hlavní autoři: ZHU, YAOHUI, COLAK, TUGBA, SHENOY, MOHAN, LIU, LIANSHENG, PAI, REETESH, LI, CUIPING, MEHTA, KSHAMA, PASRICHA, PANKAJ JAY
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522725/
https://ncbi.nlm.nih.gov/pubmed/21473865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.03.046
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