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Cost-effectiveness Analysis of Genetic Testing and Tailored First-Line Therapy for Patients With Metastatic Gastrointestinal Stromal Tumors

IMPORTANCE: Gastrointestinal stromal tumor (GIST) is frequently driven by oncogenic KIT variations. Imatinib targeting of KIT marked a new era in GIST treatment and ushered in precision oncological treatment for all solid malignant neoplasms. However, studies on the molecular biological traits of GI...

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Publicat a:JAMA Netw Open
Autors principals: Banerjee, Sudeep, Kumar, Abhishek, Lopez, Nicole, Zhao, Beiqun, Tang, Chih-Min, Yebra, Mayra, Yoon, Hyunho, Murphy, James D., Sicklick, Jason K.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522695/
https://ncbi.nlm.nih.gov/pubmed/32986105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.13565
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