Anti-KIT DNA Aptamer for Targeted Labeling of Gastrointestinal Stromal Tumor

Gastrointestinal stromal tumor (GIST), the most common sarcoma, is characterized by KIT protein overexpression, and tumors are frequently driven by oncogenic KIT mutations. Targeted inhibition of KIT revolutionized GIST therapy and ushered in the era of precision medicine for the treatment of solid...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Principais autores: Banerjee, Sudeep, Yoon, Hyunho, Yebra, Mayra, Tang, Chih-Min, Gilardi, Mara, Narayanan, Jayanth S. Shankara, White, Rebekah R., Sicklick, Jason K., Ray, Partha
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202956/
https://ncbi.nlm.nih.gov/pubmed/32127469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0959
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