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Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling

Atherosclerosis is a major reason for the high morbidity and mortality of cardiovascular diseases. Macrophage inflammation and foam cell formation are the key pathological processes of atherosclerosis. Ginsenoside compound K (CK) is a metabolite derived from ginseng. CK has anti atherosclerotic effe...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Lu, Shan, Luo, Yun, Sun, GuiBo, Sun, XiaoBo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522510/
https://ncbi.nlm.nih.gov/pubmed/33041808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.567238
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