Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling

Atherosclerosis is a major reason for the high morbidity and mortality of cardiovascular diseases. Macrophage inflammation and foam cell formation are the key pathological processes of atherosclerosis. Ginsenoside compound K (CK) is a metabolite derived from ginseng. CK has anti atherosclerotic effe...

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Vydáno v:Front Pharmacol
Hlavní autoři: Lu, Shan, Luo, Yun, Sun, GuiBo, Sun, XiaoBo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522510/
https://ncbi.nlm.nih.gov/pubmed/33041808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.567238
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