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Predicting binding sites from unbound versus bound protein structures

We present the application of seven binding-site prediction algorithms to a meticulously curated dataset of ligand-bound and ligand-free crystal structures for 304 unique protein sequences (2528 crystal structures). We probe the influence of starting protein structures on the results of binding-site...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Clark, Jordan J., Orban, Zachary J., Carlson, Heather A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522209/
https://ncbi.nlm.nih.gov/pubmed/32985584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72906-7
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