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Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures
DNA-binding proteins such as transcription factors use DNA-binding domains (DBDs) to bind to specific sequences in the genome to initiate many important biological functions. Accurate prediction of such target sequences, often represented by position weight matrices (PWMs), is an important step to u...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270014/ https://ncbi.nlm.nih.gov/pubmed/22312425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030446 |
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