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Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures

DNA-binding proteins such as transcription factors use DNA-binding domains (DBDs) to bind to specific sequences in the genome to initiate many important biological functions. Accurate prediction of such target sequences, often represented by position weight matrices (PWMs), is an important step to u...

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書誌詳細
主要な著者: Chen, Chien-Yu, Chien, Ting-Ying, Lin, Chih-Kang, Lin, Chih-Wei, Weng, Yi-Zhong, Chang, Darby Tien-Hao
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270014/
https://ncbi.nlm.nih.gov/pubmed/22312425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030446
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