Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

Alzheimer disease (AD) is a devastating neurological disease associated with progressive loss of mental skills and cognitive and physical functions whose etiology is not completely understood. Here, our goal was to simultaneously uncover novel and known molecular targets in the structured layers of...

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Vydáno v:iScience
Hlavní autoři: Navarro, José Fernández, Croteau, Deborah L., Jurek, Aleksandra, Andrusivova, Zaneta, Yang, Beimeng, Wang, Yue, Ogedegbe, Benjamin, Riaz, Tahira, Støen, Mari, Desler, Claus, Rasmussen, Lene Juel, Tønjum, Tone, Galas, Marie-Christine, Lundeberg, Joakim, Bohr, Vilhelm A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522123/
https://ncbi.nlm.nih.gov/pubmed/33083725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101556
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