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X-ray–induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner

Since the advent of protein crystallography, atomic-level macromolecular structures have provided a basis to understand biological function. Enzymologists use detailed structural insights on ligand coordination, interatomic distances, and positioning of catalytic amino acids to rationalize the under...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pfanzagl, Vera, Beale, John H., Michlits, Hanna, Schmidt, Daniel, Gabler, Thomas, Obinger, Christian, Djinović-Carugo, Kristina, Hofbauer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521648/
https://ncbi.nlm.nih.gov/pubmed/32723869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014087
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