Mediator complex subunit Med19 binds directly GATA transcription factors and is required with Med1 for GATA-driven gene regulation in vivo

The evolutionarily conserved multiprotein Mediator complex (MED) serves as an interface between DNA-bound transcription factors (TFs) and the RNA Pol II machinery. It has been proposed that each TF interacts with a dedicated MED subunit to induce specific transcriptional responses. But are these bin...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Immarigeon, Clément, Bernat-Fabre, Sandra, Guillou, Emmanuelle, Verger, Alexis, Prince, Elodie, Benmedjahed, Mohamed A., Payet, Adeline, Couralet, Marie, Monte, Didier, Villeret, Vincent, Bourbon, Henri-Marc, Boube, Muriel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521641/
https://ncbi.nlm.nih.gov/pubmed/32737196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013728
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