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Crystal structure of human Mediator subunit MED23

The Mediator complex transduces regulatory information from enhancers to promoters and performs essential roles in the initiation of transcription in eukaryotes. Human Mediator comprises 26 subunits forming three modules termed Head, Middle and Tail. Here we present the 2.8 Å crystal structure of ME...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Monté, Didier, Clantin, Bernard, Dewitte, Frédérique, Lens, Zoé, Rucktooa, Prakash, Pardon, Els, Steyaert, Jan, Verger, Alexis, Villeret, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107663/
https://ncbi.nlm.nih.gov/pubmed/30140054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05967-y
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