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Metformin suppresses Nrf2-mediated chemoresistance in hepatocellular carcinoma cells by increasing glycolysis

The diabetes drug metformin has recently been shown to possess anti-cancer properties when used with other chemotherapeutic drugs. However, detailed mechanisms by which metformin improves cancer treatment are poorly understood. Here we provide evidence in HepG2 hepatocellular carcinoma cells that me...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Cai, Liangyu, Jin, Xin, Zhang, Jiannan, Li, Le, Zhao, Jinfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521529/
https://ncbi.nlm.nih.gov/pubmed/32927432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103777
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