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Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP

Metformin plays an anti-proliferative role in tumor cells in many types of cancer. However, the correlation between metformin and sensitivity to chemotherapeutic agents in hepatocellular carcinoma (HCC) and the relevant mechanism are unclear. The present study showed that HCC patients with type 2 di...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tian, Yu, Tang, Bo, Wang, Chengye, Sun, Deguang, Zhang, Rixin, Luo, Nan, Han, Zhao, Liang, Rui, Gao, Zhenming, Wang, Liming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216793/
https://ncbi.nlm.nih.gov/pubmed/27323827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10079
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