Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP

Metformin plays an anti-proliferative role in tumor cells in many types of cancer. However, the correlation between metformin and sensitivity to chemotherapeutic agents in hepatocellular carcinoma (HCC) and the relevant mechanism are unclear. The present study showed that HCC patients with type 2 di...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Tian, Yu, Tang, Bo, Wang, Chengye, Sun, Deguang, Zhang, Rixin, Luo, Nan, Han, Zhao, Liang, Rui, Gao, Zhenming, Wang, Liming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216793/
https://ncbi.nlm.nih.gov/pubmed/27323827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10079
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