Convection Enhanced Delivery of Macromolecules for Brain Tumors

The blood brain barrier (BBB) poses a significant challenge for drug delivery of macromolecules into the brain. Convection-enhanced delivery (CED) circumvents the BBB through direct intracerebral infusion using a hydrostatic pressure gradient to transfer therapeutic compounds. The efficacy of CED is...

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Bibliografske podrobnosti
izdano v:Curr Drug Discov Technol
Main Authors: Mehta, Ankit I., Choi, Bryan D., Ajay, Divya, Raghavan, Raghu, Brady, Martin, Friedman, Allan H., Pastan, Ira, Bigner, Darell D., Sampson, John H.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521418/
https://ncbi.nlm.nih.gov/pubmed/22339074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157016312803305951
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