Evaluation of Reversed Administration Order of Busulfan (BU) and Cyclophosphamide (CY) as Conditioning on Liver Toxicity in Allogenic Hematopoietic Stem Cell Transplantation (ALL-HSCT)

Background: Busulfan (BU) in combination with cyclophosphamide (CY) is used as an effective conditioning regimen in hematopoietic SCT. Busulfan, depletes glutathione level in liver and causes elevated levels of CY metabolites. Cyclophosphamide metabolites are highly toxic for sinusoidal endothelial...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Hematol Oncol Stem Cell Res
Autori principali: Ramzi, Mani, Namdari, Nasrin, Haghighat, Shirin, Haghighinejad, Hourvash
Natura: Artigo
Lingua:Inglês
Pubblicazione: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2020
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521389/
https://ncbi.nlm.nih.gov/pubmed/33024523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18502/ijhoscr.v14i3.3725
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi