Evaluation of Reversed Administration Order of Busulfan (BU) and Cyclophosphamide (CY) as Conditioning on Liver Toxicity in Allogenic Hematopoietic Stem Cell Transplantation (ALL-HSCT)

Background: Busulfan (BU) in combination with cyclophosphamide (CY) is used as an effective conditioning regimen in hematopoietic SCT. Busulfan, depletes glutathione level in liver and causes elevated levels of CY metabolites. Cyclophosphamide metabolites are highly toxic for sinusoidal endothelial...

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Detalhes bibliográficos
Publicado no:Int J Hematol Oncol Stem Cell Res
Main Authors: Ramzi, Mani, Namdari, Nasrin, Haghighat, Shirin, Haghighinejad, Hourvash
Formato: Artigo
Idioma:Inglês
Publicado em: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521389/
https://ncbi.nlm.nih.gov/pubmed/33024523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18502/ijhoscr.v14i3.3725
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