Evaluation of Reversed Administration Order of Busulfan (BU) and Cyclophosphamide (CY) as Conditioning on Liver Toxicity in Allogenic Hematopoietic Stem Cell Transplantation (ALL-HSCT)

Background: Busulfan (BU) in combination with cyclophosphamide (CY) is used as an effective conditioning regimen in hematopoietic SCT. Busulfan, depletes glutathione level in liver and causes elevated levels of CY metabolites. Cyclophosphamide metabolites are highly toxic for sinusoidal endothelial...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Hematol Oncol Stem Cell Res
Prif Awduron: Ramzi, Mani, Namdari, Nasrin, Haghighat, Shirin, Haghighinejad, Hourvash
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521389/
https://ncbi.nlm.nih.gov/pubmed/33024523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18502/ijhoscr.v14i3.3725
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