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Overexpression of P‐glycoprotein and resistance to Imatinib in chronic myeloid leukemia patients

BACKGROUND: The P‐glycoprotein (P‐gp) is one of the mechanisms of Imatinib (IM) resistance in chronic myeloid leukemia (CML). P‐gp has been identified as an efflux pump involved in releasing of IM outside CML cells. To date, the P‐gp involvement in the IM resistance development was not completely un...

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Dades bibliogràfiques
Publicat a:J Clin Lab Anal
Autors principals: Ammar, Mariam, Louati, Nour, Frikha, Imen, Medhaffar, Moez, Ghozzi, Hanen, Elloumi, Moez, Menif, Hela, Zeghal, Khaled, Ben Mahmoud, Lobna
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521244/
https://ncbi.nlm.nih.gov/pubmed/32715517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23374
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